Effect of choline chloride in allergen-induced mouse model of airway inflammation

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Effect of choline chloride in allergen-induced mouse model of airway inflammation.

The incidence of asthma has increased the world over, and current therapies for the disease suffer from potential side-effects. This has created an opportunity to develop novel therapeutic approaches. Here, the anti-inflammatory activity of choline was investigated in a mouse model of allergic airway inflammation. Choline (1 mg.kg(-1)) was administered via oral gavage or intranasally before and...

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Title: Effect of choline chloride in allergen induced mice model of airway inflammation Short title: Anti-inflammatory action of choline in mouse model

Incidence of asthma has increased world over and current therapies for the disease suffer from potential side effects. This has created an opportunity to develop novel therapeutic approaches. Here anti-inflammatory activity of choline was investigated in mice model of allergic airway inflammation. Choline (1 mg/kg) was administered via oral gavage or intranasal (i.n.) route before and after ova...

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Vaccination with DNA encoding Dermatophagoides pteronyssinus group 2 (Der p 2) allergen previously showed its effects of immunologic protection on Der p 2 allergen-induced allergic airway inflammation in mice. In present study, we investigated whether DNA vaccine encoding Der p 2 could exert therapeutic role on allergen-induced allergic airway inflammation in mouse model and explored the mechan...

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ژورنال

عنوان ژورنال: European Respiratory Journal

سال: 2007

ISSN: 0903-1936,1399-3003

DOI: 10.1183/09031936.00019307